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   news News of medicine.
 
 

Sleep May Help Clear Brain For New Learning.

 
 

04, 2009.

A new theory about sleep's benefits for the brain gets a boost from fruit flies in the journal Science. Researchers at Washington University School of Medicine in St. Louis found evidence that sleep, already recognized as a promoter of long-term memories, also helps clear room in the brain for new learning.

 
   
 

The critical question: How many synapses, or junctures where nerve cells communicate with each other, are modified by sleep? Neurologists believe creation of new synapses is one key way the brain encodes memories and learning, but this cannot continue unabated and may be where sleep comes in. "There are a number of reasons why the brain can't indefinitely add synapses, including the finite spatial constraints of the skull," says senior author Paul Shaw, Ph.D., assistant professor of neurobiology at Washington University School of Medicine in St. Louis. "We were able to track the creation of new synapses in fruit flies during learning experiences, and to show that sleep pushed that number back down." Scientists don't yet know how the synapses are eliminated. According to theory, only the less important connections are trimmed back, while connections encoding important memories are maintained. Many aspects of fly sleep are similar to human sleep; for example, flies and humans deprived of sleep one day will try to make up for the loss by sleeping more the next day. Because the human brain is much more complex, Shaw uses the flies as models for answering questions about sleep and memory. Sleep is a recognized promoter of learning, but three years ago Shaw turned that association around and revealed that learning increases the need for sleep in the fruit fly. In a 2006 paper in Science, he and his colleagues found that two separate scenarios, each of which gave the fruit fly's brain a workout, increased the need for sleep. The first scenario was inspired by human research linking an enriched environment to improved memory and other brain functions. Scientists found that flies raised in an enhanced social environment—a test tube full of other flies—slept approximately 2-3 hours longer than flies raised in isolation. Researchers also gave male fruit flies their first exposure to female fruit flies, but with a catch—the females were either already mated or were actually male flies altered to emit female pheromones. Either fly rebuffed the test fly's attempts to mate. The test flies were then kept in isolation for two days and exposed to receptive female flies. Test flies that remembered their prior failures didn't try to mate again; they also slept more. Researchers concluded that these flies had encoded memories of their prior experience, more directly proving the connection between sleep and new memories. Scientists repeated these tests for the new study, but this time they used flies genetically altered to make it possible to track the development of new synapses, the junctures at which brain cells communicate. "The biggest surprise was that out of 200,000 fly brain cells, only 16 were required for the formation of new memories, " says first author Jeffrey Donlea, a graduate student. "These sixteen are lateral ventral neurons, which are part of the circadian circuitry that let the fly brain perform certain behaviors at particular times of day." When flies slept, the number of new synapses formed during social enrichment decreased. When researchers deprived them of their sleep, the decline did not occur. Donlea identified three genes essential to the links between learning and increased need for sleep: rutabaga, period and blistered. Flies lacking any of those genes did not have increased need for sleep after social enrichment or the mating test. Blistered is the fruit fly equivalent to a human gene known as serum response factor (SRF). Scientists have previously linked SRF to plasticity, a term for brain change that includes both learning and memory and the general ability of the brain to rewire itself to adapt to injury or changing needs. The new study shows that SRF could offer an important advantage for scientists hoping to study plasticity: unlike other genes connected to plasticity, it's not also associated with cell survival. "That's going to be very helpful to our efforts to study plasticity, because it removes a large confounding factor," says co-author Naren Ramanan, Ph.D., assistant professor of neurobiology. "We can alter SRF activity and not have to worry about whether the resulting changes in brain function come from changes in plasticity or from dying cells." Shaw plans further investigations of the connections between memory and sleep, including the question of how increased synapses induce the need for sleep. "Right now a lot of people are worried about their jobs and the economy, and some are no doubt losing sleep over these concerns," Shaw says. "But these data suggest the best thing you can do to make sure you stay sharp and increase your chances of keeping your job is to make getting enough sleep a top priority."

ScienceDaily

 
 
 
 
 
E-APTIEKA  THAT You searched, possibly HERE >>> E-Shop of Health
 
   

Čavanpraš Dabur 500g

10.00 €

 

Dabur Čavanpraš – ajurvēdisks pārtikas produkts, kurš izgatavots no augiem un augļiem ar autentisko seno formulu. Tās izgatavošanā izmanto 43 dabiskās sastāvdaļas, ieskaitot augļus un garšaugus. Čavanpraš tradicionāli ir pazīstams ar savām atjaunojošām īpašībām (galvenokārt nodrošina vitānija,  sida un tribulis). Katrai 15 g porcijai piemīt antioksidantu spēja (veicina šūnu aizsardzību pret oksidatīvo stresu) , kura  ir līdzvērtīga  500 mg C vitamīna ( 625% IDD*).

 

Neto masa : 250g (8.825 šķidruma unces); 500g (17.65 šķidruma unces); 1 kg (35,3 šķidruma unces)

Sastāvs 15 g : svaigi emblikas augļi  – 13,5 g, cukurs, medus, kausēts sviests, garais pipars, sezama eļļa, ipomeja, kardamons,bambuss, pujerārija, vitānija, sparģeļi, kanēļkoka miza, Dashmool maisījums (Gumijsveķu aigle, premna, oroksils (0,06 g) stereosperma, gmelina, Indijas naktene, dzeltenaugļu naktene (0,06 g), desmodiji, urārija, tribulis), sida, ugunsarkanās pupiņas, mungo pupiņas,pistācijas pangas, filanti, rozīnes (0,06 g), gimnēma, kālis, terminālija, kurkuma  (0,06 g), zemesmandele  (0,06 g), boerhāvija, ūdensroze, Indijas riekstkoks, lakrica, eritrīna, sandalkoks, krustnagliņas, kasijas kanēlis, Indijas dzelzskoks (0,06 g), konservants: kālija sorbāts (E 202) 0.02 g

Ieteicamā diennakts deva: 1 tējkarote (7.5g) 2 reizes dienā (kopā 15g), uzdzerot ūdeni, pienu, vai sulu. Arī var izmantot kā džemu vai lietot uz maizes. Brīdinājums: Glabāt vēsā , sausā vietā. Glabāt bērniem nepieejamā vietā. Pēc atvēršanas izlietot 10 nedēļu laikā. Piemērots veģetāriešiem. Nav piemērots diabētiķiem. Nepārsniegt ieteicamo diennakts devu. Neizmantot uztura bagātinātāju kā pilnvērtīga un sabalansēta uztura aizvietotāju. Nelietot pēc derīguma termiņa beigām. Ieteicams līdz... beigām un Partijas numuru skat. uz iepakojuma.Ražots/Fasēts : Naturelle LLC, P.O.Box:6399,Ras Al  Khaimah, U.A.E. pēc Dabur International Ltd. P.O.Box:1944, Dubai U.A.E.- Apvienotie Arābu Emirāti pasūtījuma. Pēc Dabur India Ltd., 8/3, Asif Ali Road, New Delhi - 110002, Indija licences. Izcelsmes valsts- Indija.Importētājs: Dabur International Limited , 2, Gayton Road, Harrow, Middx, HAI 2XU, UK.

Iepakojums: 500g

   

Kakla pneimatiskā apkakle

19.80 €

Kakla pneimatiskā apkakle jālieto, tad, kad parādās pirmās osteohandrozes pazīmes:
1) Dažāda veida sāpes pakauša daļā, plecos, lāpstiņu rajonā.
2) Apgrūtinātas galvas kustības.
3) Roku tirpšana jebkurā diennakts laikā.
4) Galvas sāpes, galvas reibonis, slikta dūša.
5) Meteoatkarība, bezmiegs.
6) Paaugstināts asinsspiediens, troksnis ausīs.
7) Sāpes var pāriet uz rokām, pirkstiem.

Pielietojot apkakli Jūs:
1. Uzlabojat galvas, galvas smadzeņu, muguras smadzeņu, kakla, plecu daļas apgādi ar asinīm.
2. Nostiprināt mugurkaula skriemeļus, muskuļus un saites.
3. Noņemat paaugstinātu ikdienas spriedzi uz muguru un kaklu.
4. Atjaunojat normālu roku jūtamību.
5. Atjaunojat pilnīgu galvas un kakla kustību spēju.

Pielietošanas metodika:
1. Pirms procedūras uzsākšanas ieņemiet ērtu pozīciju krēslā.
2. Aplieciet apkakli ap kaklu.
3. Atregulējiet apkakli atkarībā no kakla platuma un aizpogajiet to.
4. Aizskrūvējiet ventili pulksteņrādītāja virzienā.
5. Spiežot pumpīti, piepildiet apkakli ar gaisu līdz komfortablam stāvoklim.
6. Pirmo nedēļu ieteicams veikt pa divām 5 minūšū ilgām procedūrām dienā, pie kam apkakli stipri nepiepūšot. Pakāpeniski palieliniet procedūru laiku līdz 30 minūtēm dienā (katru nedēļu paildzinot procedūru pa 5 minūtēm) kā arī piepūšot apkakli ar vien stiprāk.
7. Pēc procedūru pabeigšanas pakāpeniski atveriet ventili uz pumpīša, lēni izlaižot gaisu no apkakles.
8. Kad no apkakles izies viss gaiss, atpogājiet un noņemiet to.
9. Pēc procedūras atpūtieties krēslā vai gultā 20-30 minūtes (neveiciet nekādas aktīvas kustības). Procedūru veikšanas kurss jāturpina no 1 līdz 3 mēnešiem (kurss tiek noteikts katram individuāli). Maksimālais laiks procedūru veikšanai- ne ilgāks par 30 minūtēm

Piesardzība:
Ja piepūšot apkakli, jūtat veiglu galvas reiboni, raibumu acīs un sliktu dūšū, lēni izlaidiet gaisu no apkakles un sakārtojiet to, ieņemiet ērtu pozīciju. Spriedzi var noņemt arī pamainot galvas stāvokli, noliecot to uz apakšu vai atliecot uz aizmuguri. Gaisu no apkakles jāizlaiž pakāpeniski, ja to dara ātri, iespējams sajutīsiet īslaicīgu galvas reiboni. Tādā gadījumā mazliet atpūtieties un diskomforts pāries. Aizliegts stiept apkakli ar spēku, apkakle, var saplīst.

Raksturojums:
1. Ērta un viegli lietojama.
2. Veicot procedūru, var ieņemt jebkuru pozu: sēdēt, gulēt.
3. Piepūšamās apkakles pielietošana ir pilnīgi droša.
4. Izstiepšanas robežas – līdz 17 cm (vertikāli).
5. Izstiepšanas spēks no 0 līdz 20kg.
6. Procedūru veikšanas laiks, izmantojot apkakli, ne vairāk par 30 min.
Ražotājs: Ķīna.

 

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